The singer and bassist says his diagnosis "sucks" and "frightens" him, and he is undergoing chemotherapy.

 He said on Twitter that he had been undergoing chemotherapy for three months and that he still had "months of treatment ahead of me... It stinks and I'm scared, but I'm fortunate to have incredible doctors, family, and friends to help me get through it."

Hoppus founded Blink-182 in the mid-1990s with vocalist-guitarist Tom DeLonge and drummer Scott Rayner, releasing their debut album, Cheshire Cat, in 1995. After Raynor was replaced as drummer, they released Enema of the State in 1999, a seminal pop-punk album that included hit singles What's My Age Again? and All the Small Things. Since then, the band has released five more albums, all of which have charted in the top three in the United States. Hoppus debuted his new project Simple Creatures in 2019, a collaboration with All Time Low's Alex Gaskarth.

Hoppus has received support from his current and former bandmates, with DeLonge saying, "He is strong, and a super-human who is pushing through this difficult obstacle with grace."